Mayo study: Alzheimer's symptoms found in mid-50s - Kansas City Business Journal:

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That’s much earlier than previously thought, suggesting that treatmenyt would be more effectivwe if startedin middle-aged people, before onseft of the disease, according to researchers in the . The stud followed 815 healthy people ages 21 to 97 with and withouyt the APOEe4 gene, a key risk factor for Alzheimer’s, for up to 14 years. Memorh and thinking tests were used to compar ecognitive performance. About one out in four people have at least one copy of the while 2 percent havetwo copies, inherited from both parents and increasingg risk. Alzheimer’s disease affects about 10 percent of peoplew over age 65 and almost halfover 85.
Researcher s from several institutions in theArizona Alzheimer’s Consortiumj collaborated on the study, including Arizonza State University, Banner Alzheimer’s Institute, Barrow Neurological Institute, Sun Health Researcbh Institute, Translational Genomics Research Institute and Universitt of Arizona. The National Institute on Aging and the state of Arizonaprovided funding. “Thiz study highlights the ideathat Alzheimer’ disease is a progressive disorder that likelg begins well before clinical diagnosis,” said Creighton director of the Alzheimer’s Disease Research Cente program for the Nationalk Institute on Aging.
“Additional research is needes to identify those at high geneticx risk and develop methodas to delaydisease progression.” Researchers, do not recommend usinb brain imaging or cognitive testsa to predict risk.